AlluraClarity
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18 peer-reviewed papers. 3840 patients. One truth.
Significantly lower dose – across clinical areas, patients and operators^a

Making the difference with Live Image Guidance

Every day we see how much of a difference we are making to the quality of people’s lives. And the spontaneous reactions just keep flowing back to us. Today the interventional community is showing us that the AlluraClarity family of X-ray systems with ClarityIQ has fulfilled its ambition and promise.

With 18 peer-reviewed papers and 3840 patients to date, this growing body of evidence reveals one truth: there is significantly lower dose across clinical areas, patients and operators.^a

18 peer-reviewed papers.
For interventional neuroradiology, interventional cardiology, interventional oncology and vascular.

Click for Neuro section

Click for Vascular section

Click for Cardiac section

18 peer-reviewed papers.
For interventional neuroradiology, interventional cardiology, interventional oncology and vascular.

Click for Neuro section

Click for Vascular section

Click for Cardiac section

Interventional neuroradiology

To date, two peer-reviewed comparative studies^1,2 have been performed on a total of 634 patients at the interventional neuroradiology department at Karolinska University Hospital in Stockholm, Sweden. Patients underwent aneurysm repair and arterior-venous malformation treatments, as well as other diagnostic and interventional neuroradiology procedures. These procedures are among the most demanding in the interventional neuroradiology world, requiring images which show very fine anatomical details.

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Findings included:

In neuro DSA, ClarityIQ technology reduces patient dose by 75% while maintaining equivalent image quality, compared to an Allura Xper system^1,c,h
In diagnostic and interventional neuro procedures, ClarityIQ technology reduces patient dose by 62% and 65%, respectively, compared to an Allura Xper system^2,c,d

This dose reduction is, at least in my mind a real quantum leap in reducing the dose and improving thereby the procedure both for the patient and for us. I think it's really fantastic."

Dr. T. Andersson, Interventional Neuroradiologist, Karolinska University Hospital, Stockholm, Sweden

Dr. M. Söderman, Sweden

Radiation dose in neuroangiography using image noise reduction technology: a population study based on 614 patients^2,c,d

Dr. M. Söderman, Sweden

Image noise reduction algorithm for digital subtraction angiography: clinical results^1,c,h

Get all peer reviewed papers for interventional neuroradiology

Interventional cardiology

To date, seven peer-reviewed comparative studies on cardiac interventions have been performed on a total of 2140 patients in various hospitals around the world. The majority were percutaneous coronary interventions. One study each has been performed for pediatric and adult congenital heart disease interventions,⁷ transcatheter aortic valve implantations (TAVIs)⁸ and electrophysiology interventions.¹³

Request all interventional cardiology papers

Findings included:

In diagnostic coronary angiography, ClarityIQ technology reduces patient dose by 75% while maintaining diagnostic image quality, compared to an Allura Xper system^4,c,e
In cardiac cine, ClarityIQ technology reduces patient dose by 53% while maintaining equivalent image quality, compared to an Allura Xper system^5,c,f
In EP procedures, ClarityIQ technology reduces patient dose by 43%, compared to an Allura Xper system^13,c,i
Significant patient dose reduction for adult congenital heart disease interventions^7,c

I think now this is the gold standard for interventional cardiology, for structural interventions – for sure. I have no doubt about that.”

Dr. Bruno Garcia, Interventional Cardiologist, Hospital Vall d’Hebron , Barcelona, Spain.

Dr. Y. Taeymans, Belgium

Novel X-ray imaging technology enables significant patient dose reduction in interventional cardiology while maintaining diagnostic image quality^4,c,e

Dr. T. ten Cate, The Netherlands

Novel X-ray image noise reduction technology reduces patient radiation dose while maintaining image quality in coronary angiography^5,c,f

Dr. L.R. Dekker, The Netherlands

New image processing and noise reduction technology allows reduction of radiation exposure in complex electrophysiologic interventions while maintaining optimal image quality: a randomized clinical trial^13,c,i

Dr. S. Nakamura, Japan

Patient radiation dose reduction using an X-ray imaging noise reduction technology for cardiac angiography and intervention^6,c

Get all peer reviewed papers for interventional cardiology

Interventional oncology and vascular

To date, nine peer-reviewed comparative studies have been performed on a total of 966 patients for diverse vascular interventions. These range from adult iliac artery and EVAR procedures to pediatric abdominal procedures. Four peer-reviewed studies have also been conducted for TACE procedures.

Request all interventional oncology and vascular papers

Findings included:

In iliac DSA, ClarityIQ technology reduces patient dose by 83% while maintaining equivalent image quality, compared to an Allura Xper system^10,c,g
In aortoiliac endovascular procedures ClarityIQ technology reduces patient dose by 72%, compared to an Allura Xper system^11,c,k
In EVAR procedures ClarityIQ technology reduces patient dose by 57% compared to an Allura Xper system^{11, c, k}
In repetitive TACE procedures, ClarityIQ technology reduces patient dose by 50% while maintaining image quality, compared to an Allura Xper system^16,c,l
The new imaging platform significantly reduced radiation exposure for TACE procedures without increased radiation time or negative impact on DSA image quality.^c,l

The results obtained herein show a substantial reduction in the dose of radiation to patients and staff in the hybrid OR suite after the introduction of the new CIQ technology without having to change the standard way of working”¹¹

Dr. M.J.L. van Strijen, The Netherlands

Evaluation of a noise reduction imaging technology: non-inferiority of image quality and patients dose reduction assessment^10,c,g

Dr. R.F.F. van den Haak, The Netherlands

Significant Radiation Dose Reduction in the Hybrid Operating Room Using a Novel X-ray Imaging Technology^11,c,k,j

Dr. R. Li, China

Novel X-Ray Imaging Technology Allows Substantial Patient Radiation Reduction without Image Quality Impairment in Repetitive Transarterial Chemoembolization for Hepatocellular Carcinoma^16,c,l

Dr. J.F. Geschwind, USA

A new angiographic imaging platform reduces radiation exposure for patients with liver cancer treated with transarterial chemoembolization¹⁵

Get all peer reviewed papers for interventional oncology and vascular

AlluraClarity with ClarityIQ technology

Significantly lower dose, across clinical areas, patients and operators. With the AlluraClarity, you can decide with confidence and peace of mind – thanks to excellent visibility at significantly lower X-ray dose.

Learn more

DoseWise Allura in all our Allura systems

Get the latest news and information about how our dose management solutions can help you lower your current X-ray dose levels and track your performance to meet new radiology dose requirements.

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SmartPath – extend the lifetime of your lab

Upgrade your existing equipment with Philips SmartPath to gain the most advanced enhancements in workflow, dose management and imaging quality with the equipment you already have.

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Radiation hazards in the interventional suite

Radiation exposure is necessary for life-saving procedures, but with it comes some risk. Patients and physicians are both exposed to high levels of radiation during fluoroscopic procedures. See some best practices for helping manage exposure.

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Footnotes
Footnotes
Philips AlluraClarity interventional X-ray system

a In 18 individual comparative studies, Philips ClarityIQ was associated with reductions in patient radiation exposure.^1-18

b Relationship between radiation exposure and risk of complications, long-term health risk, procedure time and patient characteristics, procedure complexity, as reported in medical guidelines.¹⁹

c The results of the application of dose reduction techniques will vary depending on the clinical task, patient size, anatomical location and clinical practice. The interventional radiologist assisted by a physicist as necessary has to determine the appropriate settings for each specific clinical task.

d Results based on total dose area product from a single center retrospective, historically controlled cohort study on 614 patients (302 for Allura Xper without ClarityIQ and 312 for Allura Xper with ClarityIQ). Procedural performance (fluoroscopy time and number of DSA images) of the physicians did not significantly differ between the two cohorts.²

e Results based on total dose area product from a single center, prospectively randomized cohort study on 70 consecutive patients (35 for Allura Xper without ClarityIQ and 35 for Allura Xper with ClarityIQ). Number of cine images and contrast medium did not significantly differ between the two cohorts, while fluoroscopy time was significantly higher for the ClarityIQ group. Image quality was based on subjective assessment of two cine runs selected from each patient in two specific projections. Ratings for image contrast, resolution and general appearance were not statistically different. Image noise was more apparent for ClarityIQ images.⁴

f Results based on cine dose area product per frame from a single center prospective study on 39 patients. Cine runs for Allura Xper with ClairtyIQ and Allura Xper without ClarityIQ were acquired on the same patient under same condition of geometry, field of view and injection protocol. Image quality comparison is based on subjective assessment (side-by-side, score: equal or better than the other, blinded review by 6 independent cardiologists).⁵

g Results based on DSA dose area product per frame from a single center prospective randomized study on 48 patients. DSA runs for Allura Xper with ClarityIQ and Allura Xper without ClarityIQ were randomly acquired on the same patient under same condition of geometry, field of view and injection protocol. Image quality was based on subjective assessment (side-by-side, equal or superior than the other, blinded review by 5 independent radiologists).¹⁰

h Results based on DSA dose area product per frame from a single center prospective study on 20 patients. DSA runs for Allura Xper with ClarityIQ and Allura Xper without ClarityIQ were acquired on the frontal and lateral channel on the same patient under same condition of geometry, field of view and injection protocol. Image quality was based on subjective assessment (score 1-5, 1=very poor, 5=excellent, blinded review by 3 radiologists involved in the study).¹

i Results based on total dose area product from a single center prospectively randomized cohort study on 136 patients (68 for Allura Xper without ClarityIQ and 68 for Allura Xper with ClarityIQ). Procedural performances (fluoroscopy time and number of cine images) of the physicians did not significantly differ between the two cohorts.¹³

j Results based on total dose area product from a single center prospective historically controlled cohort study on 101 patients (34 for Allura Xper without ClarityIQ and 67 for Allura Xper with ClarityIQ). Procedural performances (fluoroscopy time and contrast medium) of the physicians did not significantly differ between the two cohorts. ¹¹

k Results based on total dose area product from a single center prospective historically controlled cohort study on 37 patients (18 for Allura Xper without ClarityIQ and 19 for Allura Xper with ClarityIQ). Procedural performances (fluoroscopy time and contrast medium) of the physician did not significantly differ between the two cohorts. ¹¹

l Results based on total dose area product from a single center prospectively randomized cohort study on 50 consecutive patients randomly assigned to the Allura Xper system with ClarityIQ or Allura Xper system without ClarityIQ. Fluoroscopy time and number of DSA images did not significantly differ between the two cohorts. Fluoroscopy and DSA images of each case were subjectively assessed in blinded, offline reading (score 0-5) by three experienced interventional radiologists. DSA image quality was equally rated between cohorts, while fluoroscopy images of Allura Xper with ClarityIQ were slightly (significantly) degraded.¹⁶

Söderman M, Holmin S, Andersson T, Palmgren C, Babic D, Hoornaert B. . Image noise reduction algorithm for digital subtraction angiography: clinical results. Radiology. 2013 Nov;269(2):553-60.

Söderman M, Mauti M, Boon S, Omar A, Marteinsdóttir M, Andersson T, Holmin S, Hoornaert B. Radiation dose in neuroangiography using image noise reduction technology: a population study based on 614 patients. Neuroradiology. 2013 Nov;55(11):1365-72.

Bracken JA, Mauti M, Kim MS, Messenger JC, Carroll JD. A Radiation Dose Reduction Technology to Improve Patient Safety During Cardiac Catheterization Interventions. J Interv Cardiol. 2015 Oct;28(5):493-7.

Eloot L, Thierens H, Taeymans Y, Drieghe B, De Pooter J, Van Peteghem S, Buytaert D, Gijs T, Lapere R, Bacher K. Novel X-ray imaging technology enables significant patient dose reduction in interventional cardiology while maintaining diagnostic image quality. Catheter Cardiovasc Interv. 2015 Nov;86(5):E205-12.

Ten Cate T, van Wely M, Gehlmann H, Mauti M, Camaro C, Reifart N, Suryapranata H, de Boer MJ. Novel X-ray image noise reduction technology reduces patient radiation dose while maintaining image quality in coronary angiography. Neth Heart J. 2015 Nov;23(11):525-30.

Nakamura S, Kobayashi T, Funatsu A, Okada T, Mauti M, Waizumi Y, Yamada S. Patient radiation dose reduction using an X-ray imaging noise reduction technology for cardiac angiography and intervention. Heart Vessels. 2015 Apr 4.

Haas NA, Happel CM, Mauti M, Sahyoun C, Tebart LZ, Kececioglu D, Thorsten Laser K. Substantial radiation reduction in pediatric and adult congenital heart disease interventions with a novel X-ray imaging technology. IJC Heart & Vasculature.Volume 6, 1 March 2015, Pages 101–109

Lauterbach M, Hauptmann KE. Reducing Patient Radiation Dose With Image Noise Reduction Technology in Transcatheter Aortic Valve Procedures. Am J Cardiol. 2016 Mar 1;117(5):834-8.

De Ruiter QM, Moll FL, Gijsberts CM, van Herwaarden JA. AlluraClarity Radiation Dose-Reduction Technology in the Hybrid Operating Room During Endovascular Aneurysm Repair. J Endovasc Ther. 2016 Feb;23(1):130-8.

Van Strijen MJ, Grünhagen T, Mauti M, Zähringer M, Gaines PA, Robinson GJ, Railton NJ, van Overhagen H, Habraken J, van Leersum M. Evaluation of a noise reduction imaging technology in iliac digital subtraction angiography: noninferior clinical image quality with lower patient and scatter dose. J Vasc Interv Radiol. 2015 May;26(5):642-50.e1.

Van den Haak RF, Hamans BC, Zuurmond K, Verhoeven BA, Koning OH. Significant Radiation Dose Reduction in the Hybrid Operating Room Using a Novel X-ray Imaging Technology. Eur J Vasc Endovasc Surg. 2015 Oct;50(4):480-6.

Durrani RJ, Fischman AM, van der Bom IM, Kim E, Scott Nowakowski F, Patel RS, Lookstein RA. Radiation dose reduction utilizing noise reduction technology during uterine artery embolization: a pilot study. 2016 May-Jun;40(3):378-81.

Dekker LR, van der Voort PH, Simmers TA, Verbeek XA, Bullens RW, Veer MV, Brands PJ, Meijer A. New image processing and noise reduction technology allows reduction of radiation exposure in complex electrophysiologic interventions while maintaining optimal image quality: a randomized clinical trial. Heart Rhythm. 2013 Nov;10(11):1678-82.

Kohlbrenner R, Kolli KP, Taylor AG, Kohi MP, Fidelman N, LaBerge JM, Kerlan RK, Agarwal VK, Lehrman ED, Nanavati S, Avrin DE, Gould R. Patient Radiation Dose Reduction during Transarterial Chemoembolization Using a Novel X-Ray Imaging Platform. J Vasc Interv Radiol. 2015 Sep;26(9):1331-8.

Schernthaner RE, Duran R, Chapiro J, Wang Z, Geschwind JF, Lin M. A new angiographic imaging platform reduces radiation exposure for patients with liver cancer treated with transarterial chemoembolization. Eur Radiol. 2015 Nov;25(11):3255-62.

Wen X, Jiang X, Li R, Zhang J, Yang P, Shen B. Novel X-Ray Imaging Technology Allows Substantial Patient Radiation Reduction without Image Quality Impairment in Repetitive Transarterial Chemoembolization for Hepatocellular Carcinoma. Acad Radiol. 2015 Nov;22(11):1361-7.

Dave JK, Eschelman DJ, Wasserman JR, Gonsalves CF, Gingold EL. A Phantom Study and a Retrospective Clinical Analysis to Investigate the Impact of a New Image Processing Technology on Radiation Dose and Image Quality during Hepatic Embolization. J Vasc Interv Radiol. 2016 Apr;27(4):593-600.

Racadio J, Strauss K, Abruzzo T, Patel M, Kukreja K, Johnson N, den Hartog M, Hoornaert B, Nachabe R. dose reduction for pediatric digital subtraction angiography without impairing image quality: preclinical study in a piglet model. 2014 Oct;203(4):904-8.

Stecker, M.S., et al., Guidelines for Patient Radiation Dose Management. Journal of Vascular and Interventional Radiology, 2009. 20(7): p. S263-S273.

AlluraClarity Clinically proven

Contact information

18 peer-reviewed papers. 3840 patients. One truth. Significantly lower dose – across clinical areas, patients and operatorsa

Making the difference with Live Image Guidance

18 peer-reviewed papers. For interventional neuroradiology, interventional cardiology, interventional oncology and vascular.

18 peer-reviewed papers. For interventional neuroradiology, interventional cardiology, interventional oncology and vascular.

Interventional neuroradiology

Dr. M. Söderman, Sweden

Dr. M. Söderman, Sweden

Interventional cardiology

Dr. Y. Taeymans, Belgium

Dr. T. ten Cate, The Netherlands

Dr. L.R. Dekker, The Netherlands

Dr. S. Nakamura, Japan

Interventional oncology and vascular

Dr. M.J.L. van Strijen, The Netherlands

Dr. R.F.F. van den Haak, The Netherlands

Dr. R. Li, China

Dr. J.F. Geschwind, USA

AlluraClarity with ClarityIQ technology

DoseWise Allura in all our Allura systems

SmartPath – extend the lifetime of your lab

Radiation hazards in the interventional suite

Join the Allura family

Philips AlluraClarity interventional X-ray system

AlluraClarity
Clinically proven

18 peer-reviewed papers. 3840 patients. One truth.
Significantly lower dose – across clinical areas, patients and operators^a

18 peer-reviewed papers.
For interventional neuroradiology, interventional cardiology, interventional oncology and vascular.

18 peer-reviewed papers.
For interventional neuroradiology, interventional cardiology, interventional oncology and vascular.

Join the
Allura family